| Karolinska Institutet is looking for a PhD student for studying new treatment of growth failure and osteoporosis caused by glucocorticoids and inflammation.  | ||||
| Workplace: | Department of Women´s and Children´s Health | |||
| Department / unit or equivalent: | Pediatric Endocrinology | |||
| Form of employment: | Doctoral student | |||
| Scope: | Full-time | |||
| Time period: | The PhD project is planned to last four years. | |||
| Description of the work group/equivalent and its work/focus: | Our group focuses on pediatric growth disorders, bone growth and chondrocyte physiology. We are trying to reveal mechanism of bone elongation, its intrinsic and hormonal regulations. The research is translational, aiming for clinical applications. It involves extensive animal experiments including genetically-modified mice, tissue and cell culture and common molecular techniques. The overall scientific objective is to identify new drug targets allowing the prevention of short stature and osteoporosis caused by chronic inflammatory disorders or secondary to the treatment with glucocorticoids. We are looking for a highly motivated person with interest in pediatric endocrinology. The principal supervisor for the project is Prof. Lars Sävendahl and co-supervisors are Prof. Claes Ohlsson, Dr. Farasat Zaman, and Ass. Prof. Cecilia Aulin. This PhD project is supported by a KID grant from Karolinska Institutet. | |||
| Area of responsibilities/duties: | 1. Animal experiments including genetically-modified mice 2. Cells and organ cultures 3. Techniques for cellular and molecular biology (western blot, immunocytochemistry, immunohistochemistry, gene silencing/over expression, apoptosis assays, flowcytometry, ELISA, etc) The successful candidate is expected to play critical role in formulating scientific research hypotheses, testing the hypotheses using proper study design, analyzing the data, presenting and interpreting the results, and writing scientific reports and articles in English. | |||
| Qualifications: | To be eligible, an applicant must 1. hold a Master´s (second-cycle) degree in psychology, sociology, medicine, statistics, natural science or equivalent 2. have completed course requirements of a least 240 HECs, of which at least 60 at second-cycle level, or 3. have otherwise acquired essentially equivalent competence in Sweden or abroad. The applicant should be self-motivated, have good analytical competence, and a high capacity to work productively in a team. Fluency in English is a requirement. A strong background in molecular/cell biology and previous research experience with animal models is a plus. Knowledge in the field of bone, cartilage or inflammation research is another plus. Selection is made of highly qualified applicants on the grounds of their ability to benefit from doctoral (third-cycle) education. Karolinska Institutet applies the following assessment criteria: -Documented knowledge of significance to the research project -Analytical skills confirmed by publications or the equivalent (e.g. master thesis) -Other documented knowledge/experience of potential significance to doctoral (third-cycle) education in the subject. An overall assessment of the applicants´ qualifications will be made. The vacancy will be filled on the condition that the applicant is admitted to doctoral (third-cycle) education. For further information on doctoral education at Karolinska Institutet, see www.ki.se/doctoral | |||
| Contact: | Prof. Lars Sävendahl 08-517 723 69 lars.savendahl@ki.se | |||
| Union representatives | Lill--Britt Svensson, OFR 08-517 773 09 Lill-Britt.Svensson@ki.se | |||
| Gunnar Stenberg, SEKO 08-524 880 75 Gunnar.Stenberg@ki.se | ||||
| Lars Ährlund-Richter, SACO 08-517 734 50 Lars.Ahrlund@ki.se | ||||
| Application procedure: | Please send your application, marked with reference number: 8037/2011, to reach us by no later than January 16, 2012. The following documents should be enclosed with your application in English or Swedish: -Curriculum Vitae -Copy of degree certificate and grades -Copy of master thesis or equivalent and any previous publications -Contact information to two referees -A cover letter where you motivate your interest in the position (max. 1 page) | |||
| Application sent to: | Our online application service:or Karolinska Institutet Dep of Women´s and Children´s Health Att: Yvonne Alm Karolinska Universitetssjukhuset, H2:00 17176 Stockholm | |||
| Reference number: | 8037/2011 | |||
| Last date for applications: | January 16 2012 | |||
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