1 PhD studentship& 1 postdoctoral position in Nantes University Hospital (France)
Both positions will be in the Department of Biostatistics (EA 4275),
Nantes University Hospital (France) and in the Institute of
Transplantation, Urology and Nephrology, INSERM U643, Nantes Hospital
(France).
Our department of biostatistics is expanding with 1 professor, 3
assistant professors, 2 postdoctoral researchers and 4 PhD students. The
two main domains are the analysis of subjective data measures in Health
research, such as quality of life outcomes, and the analysis of
longitudinal and survival data in predictive medicine.
For discussion about this project, please contact Yohann Foucher (Tel: 33(0)2 40 41 28
24, Email: Yohann.Foucher@univ-nantes.fr). To candidate for one of both
following positions, you can send your CV at the previous address. You
can also send other documents as manuscripts or scientific reports.
*The Biostatistic PhD studentship*
The aim of this project is to construct a composite surrogate marker of
the long-term kidney transplant survival. Determining early surrogate
markers of long-term graft outcome is important for optimal medical
management. After the exploration of existing literature in multi-state
models and time-dependant ROC curves (or other prognostic indexes), the
PhD student will apply this methodology to the analysis of the evolution
of kidney transplant recipients (cohort DIVAT, www.divat.fr for more
details). The PhD student will propose tools for the medical community
in transplantation for improving medical decision making. Even if
simulations will first be performed in order to evaluate the robustness
of statistical methods, this project will be mainly based on real data
and close to medical practice. The capacity of the PhD student to work
within a multi-disciplinary research team will constitute a very
important issue for the candidate evaluation.
Applicants should have a master's degree in statistics with a strong
interest in medical statistics and epidemiology and also good
programming skills, specifically in R. This studentship is funded
full-time for three years by the French direction of hospitalization and
care organization (DHOS). It represents a net income of €19,000 per
year. It is open to all students from all nationalities. The project is
due to begin between the 1st October 2011 and the 1st January 2012. The
deadline for application is the 1st December 2011.
*The postdoctoral position in Biostatistics*
The aim of the survival analysis is to study the correlation between
covariates with the time until the failure of interest. The difficulty
in transplantation is to define the failure since two terminal events
are in competition: death and return in dialysis. Moreover, knowing
whether death can be considered as related or independent to
transplantation is not possible. The aim of this project is the
adaptation of survival relative models in kidney transplantation. We can
distinguish two complementary parts in this project: firstly, the
statistical developments of models and secondly, the analysis of the
cohort
DIVAT (www.divat.fr) for validation of the concept in the
transplantation community. Multi-state analysis will also constitute a
central point in the research activity.
Applicant should have a thesis in Biostatistics with a strong interest
in medical statistics and epidemiology and also good programming skills,
specifically in R. A solid theoretical background in survival and
longitudinal analysis is expected.
This studentship is funded full-time for two years by the French
national agency of research (ANR). It represents a net income of €23,000
per year. It is open to all students from all nationalities. The
project is due to begin from the 1st April 2012 (regarding availability
of the applicants). The deadline for application is the 15th February
2012.
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